Base game
- Hyperthymesiac Earn every trophy in the game 11.3%Very rare
- Creator Create a character 91.9%Common
- Consumer Make a purchase in Howard's shop 58.1%Common
- Light Napper Complete Zone 1 63.2%Common
- Deep Sleeper Reach Zone 50 12%Very rare
- Comatose Reach Zone 100 11.6%Very rare
- Novice Level up to LVL 2 70.7%Common
- Apprentice Level up to LVL 25 12.5%Very rare
- Master Level up to LVL 50 11.6%Very rare
- Choice Meat Defeat 25 Butchers with the Great Cleaver 11.6%Very rare
- Disorderly Conduct Defeat 25 Nurses with the Steel Pipe 26.7%Rare
- Hammer Time Defeat 25 Bogeymen with the Bogeyman's Hammer 11.6%Very rare
- Pyramid Scheme Defeat 25 Pyramid Heads with the Great Knife 11.7%Very rare
- Light Heal Me Use Heal Me Karma Ability to restore 25% or more health 19.1%Rare
- Light Heal You Use Heal You Karma Ability to restore 50% or more health to a friend (multiplayer) 11.7%Very rare
- Light Heal Us Use Heal Us Karma Ability to restore 50% or more health each to 3 players (multiplayer) 11.6%Very rare
- Blood Barrage Use Blood Barrage Karma Ability to kill 5 or more enemies 13.2%Very rare
- Blood Beam Use Blood Beam Karma Ability on 5 or more enemies at once 11.8%Very rare
- Blood Burn Use Blood Burn Karma Ability to damage 4 different enemy types at once 11.9%Very rare
- Power Breaker Use Weapon Breaker Power Move with a weapon that's about to shatter 12.9%Very rare
- Power Charger Use Charge Tackle Power Move to knock one enemy into another 14.1%Very rare
- Power Flasher Use Flash Burst Power Move to kill 5 or more stunned enemies in a row 12.7%Very rare
- Power Inverter Use Karma Flip Power Move to flip 8 or more enemies at once 12.3%Very rare
- Power Repeller Use Push Force Power Move to knock 8 or more enemies back at once 11.6%Very rare
- Power Savior Use Health Siphon Power Move to bring a dying friend back to life (multiplayer) 11.9%Very rare
- Power Switcher Use 360 Attack Power Move to strike 4 or more enemies at once 16.6%Rare
- Beast Master Defeat any Guardian without taking damage 13.7%Very rare
- Beat Maniac Earn a 30 or greater timed hit combo 11.5%Very rare
- Blacksmith Level up 10 different weapons 12%Very rare
- Bleeder Lose more than 400% health in one Zone without dying 27.4%Rare
- Bouncer Complete a Zone using only your fists (no weapons) 13.7%Very rare
- Brainiac Complete any 5 puzzles without using the hint lever 22.3%Rare
- Executioner Perform a timed execution on 10 enemies in one Zone 11.8%Very rare
- Klutz Trigger every kind of trap in the game 19.9%Rare
- Medic Drop a health pack after a friend requests one (multiplayer) 12.1%Very rare
- Moneybags Spend over 250,000 MR in Howard's shop 12.6%Very rare
- Ninja Complete a Zone without turning on your flashlight 31.9%Rare
- Sugar High Complete a Zone without stopping for more than 30 seconds total 13%Very rare
- Tommfoolery Perform every in-game VO clip for one character 12.4%Very rare
- Wingman Defeat any Guardian with all four players still alive (multiplayer) 11.8%Very rare
- Saint Achieve the LIGHT ending in every Forsaken Room 11.6%Very rare
- Sinner Achieve the BLOOD ending in every Forsaken Room 11.5%Very rare
- Agnostic Achieve the NEUTRAL ending in every Forsaken Room 11.6%Very rare
- Fireman Defeat the Fire Guardian 41.6%Rare
- Lumberjack Defeat the Wood Guardian 27.8%Rare
- Sandman Defeat the Light Guardian 21.1%Rare
- Plumber Defeat the Water Guardian 17.5%Rare
- Miner Defeat the Earth Guardian 16.2%Rare
- Phlebotomist Defeat the Blood Guardian 15.3%Rare
- Author Defeat the Steel Guardian and complete the game 14.7%Very rare
- Emissary Complete Valtiel's missions in Zones 1 through 21 12.5%Very rare
- Storyteller Achieve all 6 of the game's endings 11.5%Very rare
- Architect Complete your Rooms Checklist 100% 13.3%Very rare
- Antiquarian Complete your Artifacts Checklist 100% 11.5%Very rare
- Arms Dealer Complete your Weapons Checklist 100% 11.9%Very rare
- Couch Potato Complete your Broadcasts Checklist 100% 11.6%Very rare
- Librarian Complete your Notes Checklist 100% 12.3%Very rare
- Veterinarian Complete your Bestiary Checklist 100% 12%Very rare
DLC Trophies - Extra Memories Pack
DLC- Optimist Turn all 40 Change Notes to Light at the same time 10%Very rare
- Pessimist Turn all 40 Change Notes to Blood at the same time 10%Very rare
- Deity Level up to LVL 70 9.9%Very rare
- Annotator Complete the DLC (red) portions of all checklists 10%Very rare
Trophy names, descriptions and rarity come from PlayStation. Guides open on their authors' own websites.