Base game
- Does everything a spider can! Unlock all Trophies 11.5%Very rare
- Peter Parker Complete the game on human difficulty 30.4%Rare
- Vigilante Complete the game on hero difficulty 21.1%Rare
- Spider-Man Complete the game on super hero difficulty 13.8%Very rare
- On the Fly Collect all 700 Spider-Man Comic Pages 12.7%Very rare
- Librarian Collect all magazines 11.9%Very rare
- Tech Savvy Collect all hidden Tech Pieces 11.9%Very rare
- Corporate Collect all Oscorp Manuals 12%Very rare
- Journalist Collect all audio evidence 11.9%Very rare
- I'm on a Roll! Achieve a combo streak of 42 45.8%Rare
- FYI I'm Spider-Man Perform 25 Signature Moves 59.2%Common
- Haymaker Perform a Web-Rush punch 30.7%Rare
- Keep It Together Immobilize 6 enemies simultaneously with web 20.5%Rare
- Stick to the Plan Defeat 50 enemies by performing Stealth Takedowns 40%Rare
- All Tied Up Defeat 100 enemies by performing Stealth Takedowns 31.5%Rare
- Secret trophy Its name and description stay hidden until you earn it. 42.7%Rare
- Secret trophy Its name and description stay hidden until you earn it. 33.3%Rare
- Secret trophy Its name and description stay hidden until you earn it. 74.4%Common
- Secret trophy Its name and description stay hidden until you earn it. 38.6%Rare
- Secret trophy Its name and description stay hidden until you earn it. 31.6%Rare
- Clean Victory Defeat a Hunter without using your Web-Shooters 39.5%Rare
- The Sky Is the Limit Defeat the S-01 without touching the ground 13.4%Very rare
- Secret trophy Its name and description stay hidden until you earn it. 31.5%Rare
- Secret trophy Its name and description stay hidden until you earn it. 39.2%Rare
- Secret trophy Its name and description stay hidden until you earn it. 31.1%Rare
- Secret trophy Its name and description stay hidden until you earn it. 43.1%Rare
- Secret trophy Its name and description stay hidden until you earn it. 31.2%Rare
- Secret trophy Its name and description stay hidden until you earn it. 30.4%Rare
- Lightweight Champion Defeat 100 enemies 57.3%Common
- Middleweight Champion Defeat 500 enemies 33.9%Rare
- Heavyweight Champion Defeat 1000 enemies 19%Rare
- Ultimate Spider-Man Acquire all upgrades 17.2%Rare
- Sky Captain Chain 10 Web-Rushes in the city 21.6%Rare
- Sanitized Rescue all infected civilians 23%Rare
- Peace of Mind Return all escapees to the police 23%Rare
- Car Hopper Clear all car chases 20.6%Rare
- Negotiator Resolve all police deadlocks 24.6%Rare
- Call Interrupted Destroy a Seeker before it can call a Hunter 41.1%Rare
- Friendly Neighbor Save a hostage caught in a petty crime 56.2%Common
- Gladiator Complete all Oscorp Secret Research Labs 26.1%Rare
- Secret trophy Its name and description stay hidden until you earn it. 61.7%Common
- Secret trophy Its name and description stay hidden until you earn it. 34.6%Rare
Trophy names, descriptions and rarity come from PlayStation. Guides open on their authors' own websites.