Base game
- Does everything a spider can! Unlock all Trophies 13.6%Very rare
- Peter Parker Complete the game on human difficulty 34%Rare
- Vigilante Complete the game on hero difficulty 23.9%Rare
- Spider-Man Complete the game on super hero difficulty 16.2%Rare
- On the Fly Collect all 700 Spider-Man Comic Pages 14.9%Very rare
- Librarian Collect all magazines 14%Very rare
- Tech Savvy Collect all hidden Tech Pieces 14%Very rare
- Corporate Collect all Oscorp Manuals 14.1%Very rare
- Journalist Collect all audio evidence 14%Very rare
- I'm on a Roll! Achieve a combo streak of 42 47.1%Rare
- FYI I'm Spider-Man Perform 25 Signature Moves 61.7%Common
- Haymaker Perform a Web-Rush punch 34.1%Rare
- Keep It Together Immobilize 6 enemies simultaneously with web 22.9%Rare
- Stick to the Plan Defeat 50 enemies by performing Stealth Takedowns 43.2%Rare
- All Tied Up Defeat 100 enemies by performing Stealth Takedowns 34.8%Rare
- Secret trophy Its name and description stay hidden until you earn it. 46.1%Rare
- Secret trophy Its name and description stay hidden until you earn it. 36.9%Rare
- Secret trophy Its name and description stay hidden until you earn it. 76.3%Common
- Secret trophy Its name and description stay hidden until you earn it. 42.1%Rare
- Secret trophy Its name and description stay hidden until you earn it. 35.2%Rare
- Clean Victory Defeat a Hunter without using your Web-Shooters 43.7%Rare
- The Sky Is the Limit Defeat the S-01 without touching the ground 15.9%Rare
- Secret trophy Its name and description stay hidden until you earn it. 35.2%Rare
- Secret trophy Its name and description stay hidden until you earn it. 42.8%Rare
- Secret trophy Its name and description stay hidden until you earn it. 34.7%Rare
- Secret trophy Its name and description stay hidden until you earn it. 46.5%Rare
- Secret trophy Its name and description stay hidden until you earn it. 34.8%Rare
- Secret trophy Its name and description stay hidden until you earn it. 34%Rare
- Lightweight Champion Defeat 100 enemies 60.2%Common
- Middleweight Champion Defeat 500 enemies 37.7%Rare
- Heavyweight Champion Defeat 1000 enemies 22.3%Rare
- Ultimate Spider-Man Acquire all upgrades 20%Rare
- Sky Captain Chain 10 Web-Rushes in the city 23.8%Rare
- Sanitized Rescue all infected civilians 26.5%Rare
- Peace of Mind Return all escapees to the police 26.4%Rare
- Car Hopper Clear all car chases 24%Rare
- Negotiator Resolve all police deadlocks 28.2%Rare
- Call Interrupted Destroy a Seeker before it can call a Hunter 44.5%Rare
- Friendly Neighbor Save a hostage caught in a petty crime 58.6%Common
- Gladiator Complete all Oscorp Secret Research Labs 29.6%Rare
- Secret trophy Its name and description stay hidden until you earn it. 64.6%Common
- Secret trophy Its name and description stay hidden until you earn it. 38.2%Rare
Trophy names, descriptions and rarity come from PlayStation. Guides open on their authors' own websites.