Base game
- Roundgod Unlock all the other Trophies. 12.4%Very rare
- You're Hired! Complete your audition. 96.1%Common
- Flagon Rushes In Enter the Keep with the Warrior. 93.9%Common
- Shade Sneaks In Enter the Keep with the Rogue. 74.4%Common
- Fizz Pops In Enter the Keep with the Wizard. 70%Common
- Multitasker Complete a quest. 81.6%Common
- Lift Off Spend more than 2 seconds above the screen. 76.9%Common
- Seeing Red Get a red trinket from the Wheel of Wonders. 87%Common
- Blue or Bust Get a blue trinket from the Wheel of Wonders. 66.2%Common
- Going for Gold Get a gold trinket from the Wheel of Wonders. 62.4%Common
- All That Glitters Visit a treasure room. 88.9%Common
- Neat and Tidy Defeat the Organizer. 54.8%Common
- Disobedient Defeat the Disciplinarian. 58.9%Common
- Trending on Deddit Defeat the Screen Fiend. 56%Common
- The Perfect Omelette Defeat the Under Chef. 54.8%Common
- Sticky Situation Defeat the Gel Tamer. 55.7%Common
- Grand Coda Defeat the Prima Ballerina. 67.4%Common
- Hold Me Closer Help the Lonely Bard. 59.9%Common
- Ending the Reign of Cheddar Defeat the Cheddar King. 58.4%Common
- Do Not Go Gentle Defeat the Goblin Poet. 57.5%Common
- Legendary Equip a legendary item. 75.3%Common
- Eyes For You Intercept an Orc Shaman's healing magic. 61.5%Common
- Experiment Ruined Defeat the Alchemist. 75.9%Common
- Pin Cushion Get 5 projectiles stuck in you at once. 43.6%Rare
- Show Off Use skills 20 times in a room. 52.4%Common
- High Roller Get a score of 1 million gold. 27.2%Rare
- Chemistry 101 Identify all the unstable potions in a run. 71.5%Common
- Re-Un-Dead Let a lich resurrect 5 skeletons. 51%Common
- Fool Me Once Kill a Dark Elf Illusionist without hitting her mirages. 54%Common
- Feeling Sick? Get 50 stacks of poison on an enemy at once. 45.1%Rare
- Behold! The Cycloptopus! Defeat the Cycloptopus. 62.8%Common
- Can't We All Just Get Along? Defeat a Chaos room. 61.3%Common
- You Got Rocked Get petrified. 61.9%Common
- The Dad-Liest Jokes Ever, Vol.3 Insta-kill 30 enemies with Killer Joke. 25.3%Rare
- More Fun Than Bubble Wrap Pop 3 bubbles before you hit the bottom. 36.6%Rare
- Flawless Clear a room without taking damage. 38.1%Rare
- Stop Hitting Yourself Get 10 enemies to defeat each other. 49.3%Rare
- Squeaky Clean Use the clear Gelly Cube to cleanse a debuff. 63.3%Common
- Kill. Skulls. Use rune stones to crack skulls. 51%Common
- Portal Power Let the Summoners complete their ritual. 36.3%Rare
- Know It All Use each skill for each class at least once. 27.6%Rare
- Flagon Saves The Day Defeat the Giant Worm as the Warrior. 46.8%Rare
- Shade Saves The Day Defeat the Giant Worm as the Rogue. 33.2%Rare
- Fizz Saves The Day Defeat the Giant Worm as the Wizard. 29.8%Rare
- The Collector Collect all relics in the original set. 13.9%Very rare
- Grand Master Master all relics in the original set. 12.6%Very rare
Treasure Hunter Update
DLC- Puzzle Dabbler Collect enough puzzle pieces to unlock a reward. 16.2%Rare
- Great Improviser Survive to the end of a Weekly Run. 11.6%Very rare
- Payback Defeat a Treasure Chest Mimic on the first turn in a room. 44%Rare
- Tinkerer Win a run with at least ten relics equipped. 8.2%Very rare
- Made Of Magic Get your Max Mana to 200 or higher. 18.3%Rare
- Powerhouse Get your Attack to 1500 or higher. 19.8%Rare
- Total Tank Get your Max Health to 800 or higher. 19%Rare
- Hero's Dozen Level up your Hero to level 13. 11.4%Very rare
- Treasure Hunter Collect all of the Treasure Hunter relics. 7.6%Very rare
- Treasure Master Master all of the Treasure Hunter relics. 7.3%Very rare
Gift Giver Update
DLC- Refractor Defeat the Projectionist. 42%Rare
- Ice Cold Defeat the Big Freeze. 40.5%Rare
- Gracious Reward the Gift Giver's generosity. 18.4%Rare
The Druid Update
DLC- Sprig Springs In Enter the Keep with the Druid. 35.9%Rare
- Sprig Saves The Day Defeat the Giant Worm as the Druid. 16.8%Rare
- The King's Hoard Get a score of 3 million gold. 7.5%Very rare
- What's Your Hurry? Win a run in 90 shots or less. 8.4%Very rare
- Thick Skinned Get 999 barkskin on at one time. 9.2%Very rare
- Prickle Party Get 1000 total thorn stacks in a room. 7.9%Very rare
The Encore Update
DLC- Take A Bow Earn 1 Encore rose. 18%Rare
- Bravo Earn 5 Encore roses. 6.7%Very rare
- Marvelous Earn 10 Encore roses. 4.5%Ultra rare
- Standing Ovation Earn 15 Encore roses. 4%Ultra rare
- A Thrilling Performance Beat Encore 5 with any hero. 4.1%Ultra rare
- Encore Collector Collect all of the Encore relics. 4.1%Ultra rare
- Encore Master Master all of the Encore relics. 4%Ultra rare
- Juicy Target Get 35,000 gold from one potion imp. 3.9%Ultra rare
- Is This Even Legal? Get a x20 scarab multiplier. 4.1%Ultra rare
- All Of The Gold Get a score of 5 million gold. 4.2%Ultra rare
The Encore Update 2
DLC- Innoculated Defeat the Mad Virologist. 18.4%Rare
- It's Alive! Defeat the Mad Doctor. 19%Rare
- Eyes Closed Defeat Greg and Carl. 13.1%Very rare
- Why I Oughta! Defeat Bleary, Blinky, and Goo. 15%Very rare
- Cut The Power Defeat the Robotic Heart. 13.4%Very rare
- Cured Defeat the Fungal Heart. 12.2%Very rare
Trophy names, descriptions and rarity come from PlayStation. Guides open on their authors' own websites.