Base game
- Completionist Unlock all trophies 9.5%Very rare
- Mancini's Demise Complete the first episode of SiN by stopping Mancini for good. 44.9%Rare
- Bio-Mechanical Destruction Complete the second episode of SiN by destroying all of the bio-mechanical labs. 34.8%Rare
- That's My Nuke Now Complete the third episode of SiN by aborting the missile launch. 23%Rare
- Save The Water Complete the fourth episode of SiN by preventing contamination of the water supply. 28%Rare
- Chasing Elexis Complete the fifth episode of SiN by reaching the station at the end of the Mountain Gorge. 23.5%Rare
- Final Showdown Stop Elexis' operation by finishing the sixth episode of SiN and killing the Thrall Master. 21.3%Rare
- U4 & Mutants Reprise Discover why the mutants are back by finishing Wages of SiN Episode 1. 19.6%Rare
- Straight To The Point After listening to Dr. Lansing, finish Wages of SiN Episode 2. 17.4%Rare
- The Hard Way Don't listen to Dr. Lansing and finish Wages of SiN Episode 2. 11.2%Very rare
- Yamero Manero! Stop Manero's plans by finishing Wages of SiN Episode 3. 15.7%Rare
- Secret trophy Its name and description stay hidden until you earn it. 10.1%Very rare
- This Belongs In A Museum In Wages of SiN, recover the Paradox Diamond. 16.2%Rare
- Secret trophy Its name and description stay hidden until you earn it. 11.7%Very rare
- New Toy In SiN, pick up all three parts to the Pulse Rifle. 24.7%Rare
- Overkill Gib 50 enemies. 26.4%Rare
- Reduce, Reuse... Recycle? In SiN, access & shut down the recycling facility. 10.6%Very rare
- Mighty Fist Engaged Punch the lights out of 30 enemies. 26.9%Rare
- Secret trophy Its name and description stay hidden until you earn it. 32%Rare
- Nobody Suspects A Thing In SiN, don't get spotted infiltrating the SinTEK Chemical Laboratory. 16.2%Rare
- They Probably Needed These In SiN, destroy all 14 chemical drums on the dam. 25.8%Rare
- Can't... Resist... In SiN, jump down the inconspicuous whirlpool in the sewers. 16.2%Rare
- The Theorists Were Right! In Wages of SiN, discover the secret weather manipulation lab. 9.5%Very rare
- Manero's Pitch In Wages of SiN, discover Manero's pitch to protect the city in his penthouse. 11.2%Very rare
- Poof Dawg In Wages of SiN, grab at least 17 bags of Cheesy Poofs in a single playthrough. 9.5%Very rare
- Perfect Precision Land 5 headshot kills with the Sniper Rifle from more than 25 meters away. 20.2%Rare
- Bonus! In SiN, find 5 secrets. 26.9%Rare
- Something For My Troubles In SiN, find something to help fund the cops in the bank. 18.5%Rare
- Shipping? Receiving. In Wages of SiN, navigate the shipyard (either day or night) without triggering the alarms. 12.3%Very rare
- Secret trophy Its name and description stay hidden until you earn it. 10.6%Very rare
- Secret trophy Its name and description stay hidden until you earn it. 16.8%Rare
- Boxing Day Destroy 20 breakable crates containing items. 33.7%Rare
- Secret trophy Its name and description stay hidden until you earn it. 22.4%Rare
Trophy names, descriptions and rarity come from PlayStation. Guides open on their authors' own websites.