Base game
- Big Pharma Unlocked all Trophies! 4.3%Ultra rare
- Tutored Complete all the tutorial levels 28.9%Rare
- Home Remedies Complete every challenge in the Beginner scenario 9.3%Very rare
- High Street Chain Complete every challenge in the intermediate scenario 5.6%Very rare
- Big Pharmacist Complete every challenge in the Advanced scenario 4.9%Ultra rare
- On Your Marks Complete every challenge in the Quick Start scenario 4.7%Ultra rare
- Debt Buster Complete every challenge in the Crippling Debt scenario 4.6%Ultra rare
- An Expansive Achievement Complete every challenge in the Room to Maneuver scenario 4.4%Ultra rare
- Spoilt for Choice Complete every challenge in the Full Unlock scenario 4.4%Ultra rare
- Indebted Take out all three loans at the same time 15.8%Rare
- Over Analysis Successfully analyse at least 20 different effects within a single game 8.7%Very rare
- Collided! Use a Hadron Collider 10.2%Very rare
- Diversified Portfolio Simultaneously sell one Pill, Cream, Syringe and Sachet 7.7%Very rare
- Patented Simultaneously own 5 active patents 7.3%Very rare
- Land Owner Purchase every available plot on a 3x3 or larger map 6.8%Very rare
- May Contain Side-Effects Sell a product which contains four different active catalysts 4.9%Ultra rare
- The Big Three Sell a product which cures Alzheimer's Disease, Cures HIV and is a Cancer Vaccine 4.9%Ultra rare
- The Anxiety Contradiction Sell a product which Reduces Anxiety and Enocurages Anxiety 5%Ultra rare
- The Blood Pressure Contradiction Sell a product which Relieves Hypertension and Increases Blood Pressure 9.6%Very rare
- The Breathing Contradiction Sell a product which Eases Asthma and Causes Breathing Difficulties 5.5%Very rare
- The Headache Contradiction Sell a product which Eases Migraine and Causes Headaches 8.8%Very rare
- The Cancer Contradiction Sell a product which Combats Cancer and is a Carcinogenic 4.8%Ultra rare
- Expert Complete 20 challenges with an Expert rating 4.6%Ultra rare
- Master Complete 20 challenges with a Master rating 4.4%Ultra rare
- Rolling the Dice Include at least one random starting and disabled research in a custom game 6%Very rare
Trophy names, descriptions and rarity come from PlayStation. Guides open on their authors' own websites.